Cluster of Cases of the Acquired Immune Deficiency Syndrome

From the Field Services Division, Epidemiology Program Office, and the AIDS Activity, Center for Infectious Diseases, Centers for Disease Control, Atlanta, Georgia. This work was presented in part at the symposium ‘Controversies in the Management of Infectious Complications of Neoplastic Disease,” Memorial Sloan-Kettering Cancer Center, New York, New York, March 17 and 18, 1983. Requests for reprints should be addressed to Dr. William W. Darrow, AIDS Activity, Center for Infectious Diseases, Centers for Disease Control, Atlanta, Georgia 30333. The possibility that homosexual men with the acquired immune deficiency syndrome (AIDS) had been sexual partners of each other was studied. of the first 19 homosexual male AIDS patients reported from southern California, names of sexual partners were obtained for 13. Nine of the 13 patients had sexual contact with one or more AIDS patients within five years of the onset of symptoms. Four of the patients from southern California had contact with a non-Caiifornian AIDS patient, who was also the sexual partner of four AIDS patients from New York City. Uitimateiy, 40 patients in 10 cities were linked by sexual contact. Dn the basis of six pairs of patients, a mean latency period of 10.5 months (range seven to 14 months) is estimated between sexual contact and symptom onset. The finding of a cluster of AIDS patients linked by sexual contact is consistent with the hypothesis that AIDS is caused by an infectious agent.